Study Overview 
Investigator: O'Connor and Osorio Grant: NIH P51 to WNPRC and NIH R01 supplement 3R01AI116382-01A1S1 to O'Connor


ZIKV-014 tracks data in 35 datasets over 560 time points. Data is present for 3 Participants.

Study Navigator
Study Navigator

ZIKV-014 

Overview

Three animals will be subcutaneously mock-infected with PBS as control animals for our other ZIKV studies. Since the animals are sedated daily up to 10 days, the stressful effects of sedation and frequent blood draws may have an affect on clinical findings. These animals will be sedated and blood will be drawn at -6, -4, 0, 1 through 10, 14, 21, and 28 days post-mock challenge. Chemistry panels and CBCs will be run for each timepoint, and immunophenotyping, luminex, and PRNT assays will be performed to assess any potential changes to baseline readings throughout the course of the study.

Participants

  • 774011 mock-challenged with phosphate buffered saline (PBS)
  • 829256 mock-challenged with phosphate buffered saline (PBS)
  • 875914 mock-challenged with phosphate buffered saline (PBS)

Clinical and Assay Data

Viral RNA quantification

  • Plasma viral loads Chart
  • Oral swab viral loads Chart
  • Urine viral loads Chart

Clinical

Immunology


Plasma Viral Load 

Neutralizing Antibody Titers