Study Overview 
Investigator: O'Connor and Osorio Grant: NIH P51 to WNPRC and NIH R01 supplement 3R01AI116382-01A1S1 to O'Connor


ZIKV-006 tracks data in 34 datasets over 453 time points. Data is present for 2 Participants.

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Study Navigator

ZIKV-006 

Primary objectives

  • Assess whether fetal development is impacted by maternal infection with French Polynesian Zika virus during the third pregnancy trimester

Study design

Two pregnant Indian-origin rhesus macaques (early 3rd trimester) will be challenged subcutaneously with 10E4 PFU French Polynesian Zika virus.

Result summary

Two pregnant rhesus macaques were infected with Zika virus on April 25, 2016

Participants

  • 357676 challenged with 10E4 PFU Zika virus/H.sapiens-tc/FRA/2013/FrenchPolynesia-01_v1c1
  • 598248 challenged with 10E4 PFU Zika virus/H.sapiens-tc/FRA/2013/FrenchPolynesia-01_v1c1

Clinical and Assay Data

Viral RNA quantification

  • Plasma viral loads Chart
  • Pan urine viral loads Chart
  • Oral swab viral loads Chart
  • Aminocentesis viral loads Chart

Clinical

Immunology

Ultrasounds Data

Fetectomy Tissues Data | Histopathology


Ultrasounds 
Grid ViewsReportsChartsExportPrintPaging
Participant ID
Date
Comments
File Name
Days Post Gestation
Days Post Challenge
3576762016-05-03SummaryZIKV006_357676_5.3.26_summary.jpg112.08.0
3576762016-05-03HeartbeatZIKV006_357676_5.3.26_heartbeat.jpg112.08.0
3576762016-05-03PlacentaZIKV006_357676_5.3.26_placenta2.jpg112.08.0
3576762016-05-03PlacentaZIKV006_357676_5.3.26_placenta.jpg112.08.0
3576762016-05-03HC-BPDZIKV006_357676_5.3.26_HC-BPD.jpg112.08.0
3576762016-05-03Femur LengthZIKV006_357676_5.3.26_femur_length.jpg112.08.0
3576762016-05-03CerebellumZIKV006_357676_5.3.26_Cerebellum.jpg112.08.0
3576762016-05-10BPD/HCZIKV_006_5.10.16_357676_IM-0001-0008.jpg119.015.0
3576762016-05-10HeartbeatZIKV_006_5.10.16_357676_IM-0001-0010.jpg119.015.0
3576762016-05-10Femur LengthZIKV_006_5.10.16_357676_IM-0001-0014.jpg119.015.0
3576762016-05-10SummaryZIKV_006_5.10.16_357676_IM-0001-0016.jpg119.015.0
3576762016-05-17HeartbeatZIKV_006_357676_IM-0001-0001.jpg126.022.0
3576762016-05-17BPD/HCZIKV_006_357676_IM-0001-0002.jpg126.022.0
3576762016-05-17FemurZIKV_006_357676_IM-0001-0007.jpg126.022.0
3576762016-05-17SummaryZIKV_006_357676_IM-0001-0011.jpg126.022.0
3576762016-05-24HeartrateZIKV_006_5_24_2016_357676_Heartrate_IM-0001-0006.jpg133.029.0
3576762016-05-24Femur LengthZIKV_006_5_24_2016_357676_FL_IM-0001-0003.jpg133.029.0
3576762016-05-24PlacentaZIKV_006_4_19_2016_357676_Placenta_IM-0001-0008.jpg133.029.0
3576762016-05-24HeartrateZIKV_006_4_19_2016_357676_Heartrate_IM-0001-0015.jpg133.029.0
3576762016-05-24Femur lengthZIKV_006_4_19_2016_357676_FL_IM-0001-0014.jpg133.029.0
3576762016-05-24BPD/HCZIKV_006_4_19_2016_357676_BPD_HC_IM-0001-0006.jpg133.029.0
3576762016-05-24BPD/HCZIKV_006_5_24_2016_357676_BPD_HC_IM-0001-0001.jpg133.029.0
3576762016-06-07SummaryIM-0001-0017_ZIKV_006_357676_summary.jpg147.043.0
3576762016-06-07PlacentaIM-0001-0016_ZIKV_006_357676_placenta.jpg147.043.0
3576762016-06-07FLIM-0001-0008_ZIKV_006_357676_FL.jpg147.043.0
3576762016-06-07Heart RateIM-0001-0006_ZIKV_006_357676_HeartRate.jpg147.043.0
3576762016-06-07BPD_HCIM-0001-0004_ZIKV_006_357676_BPD_HC.jpg147.043.0
5982482016-05-03SummaryZIKV006_598248_5.3.16_summary.jpg127.08.0
5982482016-05-03PlacentaZIKV006_598248_5.3.16_placenta.jpg127.08.0
5982482016-05-03HeartbeatZIKV006_598248_5.3.16_heartbeat.jpg127.08.0
5982482016-05-03HC-BPDZIKV006_598248_5.3.16_HC-BPD.jpg127.08.0
5982482016-05-03Femur LengthZIKV006_598248_5.3.16_femur_length.jpg127.08.0
5982482016-05-10BPD/HCZIKV_006_5.10.16_598248_IM-0001-0003.jpg134.015.0
5982482016-05-10Femur LengthZIKV_006_5.10.16_598248_IM-0001-0007.jpg134.015.0
5982482016-05-10SummaryZIKV_006_5.10.16_598248_IM-0001-0019.jpg134.015.0
5982482016-05-17BPD/HCZIKV_006_598248_IM-0001-0002.jpg141.022.0
5982482016-05-17FemurZIKV_006_598248_IM-0001-0005.jpg141.022.0
5982482016-05-17PlacentaZIKV_006_598248_IM-0001-0006.jpg141.022.0
5982482016-05-17HeartbeatZIKV_006_598248_IM-0001-0001.jpg141.022.0
5982482016-05-17SummaryZIKV_006_598248_IM-0001-0010.jpg141.022.0
5982482016-05-24Femur LengthZIKV_006_5_24_2016_598248_FL_IM-0001-0005.jpg148.029.0
5982482016-05-24BPD/HCZIKV_006_5_24_2016_598248_BPD_HC_IM-0001-0002.jpg148.029.0
5982482016-05-24PlacentaZIKV_006_4_19_2016_598248_Placenta_IM-0001-0018.jpg148.029.0
5982482016-05-24HeartrateZIKV_006_4_19_2016_598248_Heartrate_IM-0001-0001-0002.jpg148.029.0
5982482016-05-24Femur LengthZIKV_006_4_19_2016_598248_FL_IM-0001-0006.jpg148.029.0
5982482016-05-24HeartrateZIKV_006_5_24_2016_598248_Heartrate_IM-0001-0006.jpg148.029.0
5982482016-05-24BPD/HCZIV_006_4_19_2016_598248_BPD_HC_IM-0001-0001-0001.jpg148.029.0

Key Data: plasma viral loads 

Key data: Amniocentesis viral loads 

Neutralizing Antibody Titers 

Messages 
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Re-breeding follow up
lgomes 2017-08-22
598248 participant: birth on 03-09-2017 by c-section 6 days early
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