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Histopathology tissues mmohns  2016-08-26
 
Approximately 60 tissues were fixed and analyzed following fetal necropsy for ZIKV-003, ZIKV-005, and ZIKV-006. Tissues were graded using the severity values below. Each positive tissue has a link for a description of histopathological findings from our pathology team at WNPRC. Comparative tissue images are pending and will be added to these links shortly.

ValueSeverity
0
Normal
1
Minimal
2
Mild
3
Moderate
4
Severe


Tissue
Animal 598248
Animal 357676
Animal 827577
Animal 660875
Maternal Spleen
0
3
Materna Liver
0
0
0
0
Materna Lymph Node
0
0
0
0
Placenta
0
3
Decidua
1
3
Placental Bed
0
0
0
0
Umbilical cord
0
0
0
0
Amniotic Membrane
0
Chorionic Membrane
1
Mammary Gland
0
0
0
0
Axillary Lymph Node
0
0
0
0
Forearm - skin, subq, vessels, muscle
0
0
0
0
Skin Thighs
0
0
0
0
Submandibular LN
0
0
0
0
Submucosal Salivary Gland
0
0
0
0
Buccal Mucosa
0
0
0
0
Sternum
0
0
0
0
Thymus
0
0
0
0
Pericardium
0
0
0
Heart
0
0
0
0
Aorta - Thoracic
0
0
0
0
Tongue
0
0
0
0
Tonsils
0
0
0
0
Thyroids
0
0
0
0
Esophagus
0
0
0
0
Trachea
0
0
0
0
Lung
3
Spleen
0
2
Pancreas
0
0
0
0
Pancreatic Lymph Node
0
0
0
Mesocolonic Lymph Node
0
0
0
0
Mesenteric Lymph Node
0
0
0
0
Liver
0
0
1
Kidney
0
0
0
0
Adrenal Glands
0
0
0
0
Urinary Bladder
0
0
0
0
Testis/Ovary
0
0
0
0
Seminal Vesicle/Prostate/Uterus
0
0
0
h
0
Gastric Lymph Node
0
0
0
Stomach
0
0
0
0
Duodenum
0
0
0
0
Jejunum
0
0
0
0
Ileum
0
0
0
0
Colon
0
0
0
0
Internal Iliac artery & Vein
0
0
0
0
Aorta - Abdominal
0
0
0
0
Dura Mater
0
0
0
0
Brain
0
0
0
0
Pituitary
0
0
0
0
Eye
0
0
0
3
Spinal Cord - Cervical
0
0
0
0
Spinal Cord - Thoracic
0
0
0
0
Spinal Cord - Lumbar
0
0
0
0
Saphenous Vein
0
0
0
0
Quadriceps
0
0
0
0
Femoral Bone
0
0
0
0
Bone Marrow
0
0
0
0
Femoral Head
0
0
0
0